Immortal Strands? Give Me a Break
نویسنده
چکیده
The "immortal strand" hypothesis proposes that asymmetrically dividing stem cells selectively retain chromosomes containing "old" DNA to prevent accumulation of mutations. As I describe in this Essay, such a possibility seems unlikely. An alternative explanation is that asymmetric cell divisions and cell fate are codirected by epigenetic differences between sister chromatids.
منابع مشابه
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عنوان ژورنال:
- Cell
دوره 129 شماره
صفحات -
تاریخ انتشار 2007